Vernoff is currently a member of the creative team at the popular drama Grey's Anatomy. She is credited as an executive producer, and has also written several episodes of the show. An episode Vernoff wrote, "Into You Like a Train", was nominated for a Best Writing Emmy Award. Vernoff is credited with the introduction of the catchphrase, "seriously" into the dialogue of Grey's Anatomy episodes. Series creator Shonda Rhimes says that Vernoff used it frequently in the writer's room, and "said correctly, it can convey sarcasm, dismay, disbelief, a sense of moral and ethical superiority, and gentle chastising punishment, all at once."
- She's the daughter of Bob Verne.
- Vernoff is also a playwright; a production of her play "Me, My Guitar, and Don Henley" opened in October 2006 in an off-Broadway theater.
- She was born in 1972.