Various well known actors, actresses and non-binary artists guest starred on Charmed. As a guest stars, they portray a pivotal role in the cast. They're different from extras and regular performers who have minor roles on the series. They're usual credited after the Opening, during the sequences showing parts of San Francisco, while a song is reproduced in the background, unless otherwise stated.
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A
- Aaron Lustig
- Adam Hendershott
- Adrian Paul
- Adrienne Wilkinson
- Al Rodrigo
- Al Sapienza
- Alan Wilder
- Alana de la Garza
- Alastair Duncan
- Alex Black
- Alex Breckenridge
- Alex Fernandez
- Alex McArthur
- Alex Mendoza
- Alla Korot
- Allan Louis
- Allen Cutler
- Allison Munn
- Amir Aboulela
- Amy Adams
- Amy Laughlin
- Andres Saenz-Hudson
- Andrew Bowen
- Andrew Ducote
- Andrew Jackson
- Andrew James Allen
- Andy Mackenzie
- Angela Little
- Ann Cusack
- Annabelle Gurwitch
- Anne Dudek
- Anne Haney
- Anthony Cistaro
- Anthony Denison
- Anthony Starke
- Antonio Jaramillo
- Antonio Sabàto Jr.
- Arjay Smith
- Armando Valdes
- Armin Shimerman
- Arnold Vosloo
- Ashley Gardner
- Audrey Wasilewski
- Austin Peck
B
- Bailey Chase
- Balthazar Getty
- Barbara Niven
- Barbara Pilavin
- Barbara Stock
- Bart McCarthy
- Becki Newton
- Becky Wahlstrom
- Ben Guillory
- Benjamin Parrillo
- Bernie Kopell
- Bert Rosario
- Bethany Joy Lenz
- Betsy Randle
- Beverly Sanders
- Bianca Chiminello
- Billy Drago
- Billy Jayne
- Billy Kay
- Billy Wirth
- Billy Zane
- Blake Bashoff
- Bobby Edner
- Bobby Preston
- Bodhi Elfman
- Bonnie Root
- Booker T. Huffman
- Boti Ann Bliss
- Brad Greenquist
- Brad Hawkins
- Brad Tatum
- Brandon Quinn
- Brandscombe Richmond
- Brenda Bakke
- Brett Rice
- Brian Howe
- Brian Krause
- Brian Leckner
- Brian Mulligan
- Brian Thompson
- Brian Wedlake
- Brigid Brannagh
- Brooke Nevin
- Bruce Campbell
- Bruce Gray
- Bruce Payne
- Bruno Gioiello
- Buff Bagwell
- Bug Hall
- Béatrice Rosen
C
- Cameron Bancroft
- Camilla Rantsen
- Caprice Benedetti
- Carel Struycken
- Carlos Gómez
- Carolyne Lowery
- Chad Allen
- Chad Gabriel
- Chad Willett
- Channon Roe
- Charisma Carpenter
- Charles Chun
- Charles Emmett
- Charles Robinson
- Charles Walker
- Charlie Shanian
- Charlie Weber
- Cheryl Ladd
- Chris Diamantopoulos
- Chris Flanders
- Chris Payne Gilbert
- Chris Sarandon
- Chris Spencer
- Christie Lynn Smith
- Christina Carlisi
- Christine Healy
- Christopher Cazenove
- Christopher Darga
- Christopher Neiman
- Christopher Shea
- Christopher Wiehl
- Cindy Ambuehl
- Claire Rankin
- Clare Carey
- Clarissa Romano
- Clayton Rohner
- Cleavant Derricks
- Cleo King
- Clyde Kusatsu
- Colby French
- Colin Egglesfield
- Colleen Porch
- Coolio
- Cork Hubbert
- Costas Mandylor
- Courtney Gains
- Craig Robert Young
- Cristine Rose
- Crystal Kwon
- Cullen Douglas
- Cynthia King
D
- Dakin Matthews
- Dan Gauthier
- Dana Ashbrook
- Daniel Dae Kim
- Daniel Escobar
- Daniel Hagen
- Danielle Harris
- Danielle Savre
- Danielle Weeks
- Danneel Harris
- Danny Woodburn
- Darin Heames
- Darren Pettie
- David Anders
- David Carradine
- David Chisum
- David Dayan Fisher
- David Figlioli
- David Haydn-Jones
- David Kriegel
- David Meunier
- David Netter
- David Pressman
- David Ramsey
- David Reivers
- David S. Lee
- David Starzyk
- David Wells
- Davis Gaines
- Dax Griffin
- Dean Norris
- Dean Shelton
- Deanna Russo
- Debbi Morgan
- Deborah Kellner
- Deeny Consiglio
- Denise Dowse
- Dennis Cockrum
- Derek Magyar
- Derrick McMillon
- Desmond Askew
- Diane Salinger
- Dominic Fumusa
- Don Swayze
- Dona Hardy
- Donn Swaby
- Dorian Brown
- Drew Fuller
- Drew Wood
- Dwier Brown