The American Museum of Natural History is a museum located in San Francisco, California.
Prue Halliwell worked at the museum for an undetermined amount of time. The museum was also the place she met her former fiancé Roger, who was in charge of her department. In 1998, shortly after becoming a witch, Prue got into an argument with Roger over an art exhibition that Prue secured. According to Roger, the board wanted someone more qualified to handle the collection, which meant he was taking over. Prue became frustrated with him and later decided to quit and end her engagement.